A repository of human immune profiling data and resources
HIPC
@hipcProject
One key addition is that study authors conclusions about immune signatures are linked to data. Our researcher Kerstin Westendorf (from @lji ) explains poster at #aai2024 about updates to the curation of study data on #immunology at http://immunespace.org
HIPC
@hipcProject
HIPC
@hipcProject
HIPC
@hipcProject
10 amazing women in STEM and in our collaboration
@EdlowLab
@SesmaLab
@VivianaSimonLab
@RuthMontgomery1
@MiriamMerad
@DonnaFarber3
@LungDrC
@camilahcoelho
@VirusesImmunity
@HarrisProgram
++ #womeninSTEM Keep it going.
ImmuneSpace serves as the homepage of the Human Immunology Project Consortium (HIPC), established by the NIAID Division of Allergy, Immunology, and Transplantation. HIPC centers characterize human immune responses using systems-level immune profiling technologies. ImmuneSpace makes these data available and provides tools to query and analyze it.
ImmuneSpace provides access to data on human immune responses resulting from perturbations such as vaccination, infection, medication and immune mediated diseases.
ImmuneSpace merges data from multiple sources including databases such as ImmPort and GEO/SRA along with manually curated information on detailed study design, conclusions (signatures). It’s goal is to interlink the data and provide seamless access.
The data access interface allows to filter on study criteria such as sample types, experiments performed, human subject demographics and so on.
All data is freely available for download and analysis
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172
Studies
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120
Diseases
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870K+
Assays
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28
Curated Signatures
Last updated: August 2024
ImmuneSpace provides access to multiple resources, such as Data Standards that specify a format and validation scheme for different types of experimental data.
The HIPC-Signature-Projects have performed cross-center meta-analysis of vaccine induced immune signatures.
Modules provide groupings of experimental readouts across experimental modalities that have been found to be linked.
ImmuneSpace tracks publications that are included in the data access and those published by HIPC centers. Query publications by keywords, linked data content, and source to get an overview of what is available.
Publications
Publications with exclusive ImmuneSpace data
Citations (source Web of Science)
Last updated: September 2024
The discussion forum offers announcements regarding the HIPC Centers, information on conferences, and other relevant information.
It serves as a platform to foster collaboration within the research community and facilitate discussions among researchers. We also encourage users to provide feedback (about the website or others) on the discussion forum.
The current HIPC Program is carried out by 8 centers located across the US that study immune perturbations in well-characterized human cohorts using a variety of assays including genomics, transcriptomics, proteomics, metabolomics and immune receptor repertoire sequencing.
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3
Rounds of HIPC
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8
Current centers
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2010
Human Immunology Project Consortium started
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NIAID
Funded
